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Crohn’s Disease
How Can Stem Cells Treat Crohn’s Disease?
Anyone suffering from Crohn’s disease knows the physical and emotional challenges of coping with this disease. Symptoms such as fatigue, pain, and cramps can be severe. But constant digestive distress can make it difficult to even leave the house. Although patients may experience months without symptoms, they can flare up again—suddenly and without warning.
Crohn’s disease is an inflammatory bowel disease that causes chronic inflammation of the GI tract and can affect the entire body. It can cause kidney stones and anemia—as well as interfere with absorption of essential nutrients. Medications and biologics may be effective but may cause side effects and lose effectiveness over time. For some patients, gastrointestinal surgery—which can be a complex procedure—may be a last resort.
Apply Today 1-888-567-2469Scientific Research Supports
The application of stem cell therapies in treating Crohn’s disease, thanks to their regenerative properties, anti-inflammatory effects, immune system modulating capacity, pain relief capabilities, and potential to halt Crohn’s disease progression.
World Leader in Cell Therapy
Advanced cell therapy offers new hope to patients with Crohn’s disease when standard treatments and medications may provide only temporary relief or no relief at all. At BioXcellerator, our therapies and protocols, personalized for each patient, can help:
- Promote healing of gastrointestinal tissue
- Decrease inflammation
- Alleviate pain and discomfort
- Reduce abdominal cramping and frequency of bowel movements
- Modulate the immune system
- Increase appetite and nutrient absorption
- Improve quality of life
New Treatment Options to Improve Digestive Function
Enjoy a more active life with less pain and discomfort, more energy, and improved health. Discover how cell therapy can help many patients who once lost hope get relief from symptoms of Crohn’s disease.
- Carvello, M., Lightner, A., Yamamoto, T., Kotze, P. G., & Spinelli, A. (2019). Mesenchymal Stem Cells for Perianal Crohn’s Disease. Cells, 8(7), 764. Available from: https://doi.org/10.3390/cells8070764
- Zhang, J., Lv, S., Liu, X., Song, B., & Shi, L. (2018). Umbilical Cord Mesenchymal Stem Cell Treatment for Crohn’s Disease: A Randomized Controlled Clinical Trial. Gut and liver, 12(1), 73–78. Available from: https://doi.org/10.5009/gnl17035
- Cao, Y., Su, Q., Zhang, B. et al. Efficacy of stem cells therapy for Crohn’s fistula: a meta-analysis and systematic review. Stem Cell Res Ther 12, 32 (2021). Available from: https://doi.org/10.1186/s13287-020-02095-7
- Ciccocioppo, R., Cangemi, G. C., Kruzliak, P., Gallia, A., Betti, E., Badulli, C., Martinetti, M., Cervio, M., Pecci, A., Bozzi, V., Dionigi, P., Visai, L., Gurrado, A., Alvisi, C., Picone, C., Monti, M., Bernardo, M. E., Gobbi, P., & Corazza, G. R. (2015). Ex vivo immunosuppressive effects of mesenchymal stem cells on Crohn’s disease mucosal T cells are largely dependent on indoleamine 2,3-dioxygenase activity and cell-cell contact. Stem cell research & therapy, 6(1), 137. Available from: https://doi.org/10.1186/s13287-015-0122-1
- Bernardi, L., Santos, C., Pinheiro, V., Oliveira, R. J., & Antoniolli-Silva, A. (2019). Transplantation Of Adipose-derived Mesenchymal Stem Cells In Refractory Crohn’s Disease: Systematic Review. Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 32(4), e1465. Available from: https://doi.org/10.1590/0102-672020190001e1465
- Gallo, G., Tiesi, V., Fulginiti, S., De Paola, G., Vescio, G., & Sammarco, G. (2020). Mesenchymal Stromal Cell Therapy in the Management of Perianal Fistulas in Crohn’s Disease: An Up-To-Date Review. Medicina (Kaunas, Lithuania), 56(11), 563. Available from: https://doi.org/10.3390/medicina56110563
- Grim, C., Noble, R., Uribe, G., Khanipov, K., Johnson, P., Koltun, W. A., Watts, T., Fofanov, Y., Yochum, G. S., Powell, D. W., Beswick, E. J., & Pinchuk, I. V. (2021). Impairment of Tissue-Resident Mesenchymal Stem Cells in Chronic Ulcerative Colitis and Crohn’s Disease. Journal of Crohn’s & colitis, 15(8), 1362–1375. Available from: https://doi.org/10.1093/ecco-jcc/jjab001
- Włodarczyk, M., Czerwińska, K., Włodarczyk, J., Fichna, J., Dziki, A., & Dziki, Ł. (2021). Current Overview on the Use of Mesenchymal Stem Cells for Perianal Fistula Treatment in Patients with Crohn’s Disease. Life (Basel, Switzerland), 11(11), 1133. Available from: https://doi.org/10.3390/life11111133
- Dailey, F. E., Turse, E. P., Naseer, M., Bragg, J. D., & Tahan, V. (2018). Review of stem cells as promising therapy for perianal disease in inflammatory bowel disease. World journal of transplantation, 8(4), 97–101. Available from: https://doi.org/10.5500/wjt.v8.i4.97
- Martínez-Montiel, M., Gómez-Gómez, G. J., & Flores, A. I. (2014). Therapy with stem cells in inflammatory bowel disease. World journal of gastroenterology, 20(5), 1211–1227. Available from: https://doi.org/10.3748/wjg.v20.i5.1211
- Grégoire, C., Lechanteur, C., Briquet, A., Baudoux, É., Baron, F., Louis, E., & Beguin, Y. (2017). Review article: mesenchymal stromal cell therapy for inflammatory bowel diseases. Alimentary pharmacology & therapeutics, 45(2), 205–221. Available from: https://doi.org/10.1111/apt.13864
Enjoy a better life with fewer symptoms. Find out if treatment is right for you. Schedule a free consultation with one of our experts today.
Signature Cells
Proprietary Protocols. Based on Advanced Science.
The most effective cell therapy starts with the best possible cells. BioXcellerator Signature Cells are produced from mesenchymal stem cells (MSCs) derived from Wharton’s jelly umbilical cord tissue.
Then, based on our proprietary protocols, these cells are cultured and expanded in our on-site lab—and tested to make sure they meet high standards for purity and potency and demonstrate:
- High levels of anti-inflammatory properties
- The best potential to modulate the immune system
- More potential to stimulate healing
Discover how Signature Cells and our advanced treatment protocols can ease pain, reduce inflammation, and relieve symptoms of Crohn’s disease for many patients—even those who have been suffering for many years.
Real People. Real Results.
Meet patients who now enjoy better health, more energy, and less pain and who get more out of life thanks to advanced cell therapy for Crohn’s disease and other gastrointestinal disorders.
Michael Padilla
BioXcellerator Patient
Treated for Ulcerative Colitis
They treat your physical condition and your spiritual condition. It’s an all-encompassing, full treatment, not just stem cells. It’s the quality of the stem cells that are available here; it’s the personalized service that you get here that I couldn’t get in the United States. This office would be considered grossly overstaffed in the United States. They have the right amount of people here to take care of your concerns. The level of expertise has really blown me away.
Colby Baughan
BioXcellerator Patient
Treated for Crohn’s Disease
I’ve had chronic Crohn’s Disease since I was nine. And I’ve tried every medication possible. I’ve read that stem cells can help and searched for how to get the best cells. BioXcellerator came up everywhere. And I’ve had some friends come here who’ve had amazing results. I’ll be back because I’ve got issues with my ankles and back and I want to get my life back—go after my goals and dreams. People here are very friendly and knowledgeable. Any question you have, they’ve got an answer, and they’re very caring.
Kevin Feng
BioXcellerator patient
Treated for Crohn’s Disease
This is a stressful disorder and there’s no cure for it. My entire body was inflamed. You also can’t eat. So I was literally eating boiled, blended cauliflower and carrots almost two months in a row. After treatment, I felt effects starting actually just two weeks in. I noticed my inflammation just going down. Within three or four months I was almost close to back to normal. I put on about probably close to 25 or 30 pounds, mostly just muscle weight. It’s fantastic.
