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What is Parkinson’s disease?

Parkinson’s disease is a chronic, progressive movement disorder associated with the abnormal functioning of the central nervous system. The disease comes under a group of conditions known as motor system disorder. The disease is expressed due to the loss of dopamine-producing brain cells.

How prevalent is Parkinson’s disease? 

The Center for Disease Control estimates that the age-adjusted death rate for the disease has increased drastically from 2000 to 2015. The death rate for males suffering from the disease was 8.8 per 1,000,000 population at the end of 2000. This increased to 13.5 by the end of 2014. Similarly, the death rate of females suffering from the disease was 3.9 at the end of 2000. This represents an increase to 4.8 by the end of 2014.

The data indicate that men are more prone to the disease compared to females. On the basis of the ethnicity of the individual, it is evidently concluded that the disease is more prevalent in Caucasians than other races.

The human brain is the principal organ, controlling all mechanisms such as movement, memory, speech, vision, etc. This control can be acquired by the passage of different signals to the different organs of the body. These signals are generated in the brain, passed on to the different organs via brain cells known as the neurons. These signals are passed on from one neuron to the other organs of the body with the help of the neurotransmitters. Dopamine is one of the different kinds of neurotransmitter which is found to be absent in patients with the Parkinson’s disease. This dopamine is degenerated due to the deposition of proteins or lewy bodies surrounding the neurons. These lewy bodies thus interrupt the transmission of signals due to loss of dopamine leading to the progressive degeneration of motor neurons.

Thus, in patients with the disease, the motor coordination is affected to the great extent.

How Stem Cells treatment can help.

Stem cells are the mother cells that are responsible for developing an entire human body from tiny two-celled embryos due to their unlimited ability to divide and their strong power to differentiate into all cells of different lineage. This power of stem cells has been harnessed by our technology to isolate them outside the human body, concentrate in a clean environment and implant back.

Thus, stem cells treatment involves administration of concentrated cells in the targeted area, wherein they can colonize in the damaged area, adapt the properties of resident stem cells and initiate some of the lost functions that have been compromised by the disease or injury.
Data accumulated from years of research indicate an evidence-based differentiation of stem cells into dopamine producing-neurons.

Treatment of Parkinson’s at BioXcellerator.

Intrathecal Administration – Through this mode, cells are infused in the cerebrospinal fluid through the subarachnoid spaces of the spinal canal.
Intravenous Administration – Through this mode, cells are infused through the veins along with the mannitol to expand blood volumes in the central nervous system, to ensure that the maximum number of cells are reaching to the targeted area.

Once infused back in the body, these cells can be repopulated at the damaged parts of the brain, through their strong paracrine effects and differentiate into lost dopaminergic neurons or other damaged supporting cells to improve motor functions of the brain.

Thus with our standardized, broad-based and holistic approach, it is now possible to obtain noticeable improvements in patients with Parkinson’s Disease, in the symptoms as well as functionality.

Tag: auto-immune

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