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Autoimmune & Degenerative Diseases

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An autoimmune disease are conditions in which your immune system mistakenly attacks your body. The immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them. Normally, the immune system can tell the difference between foreign cells and your own cells however in an autoimmune disease, your system generates cellular and antibody responses to substances and tissues normally present in the body. As a result of this immune response, damage to different organs and tissues occurs.

Traditional treatment methods focus on reducing normal immune system activity, often impacting other aspects of overall health and mobility. The use of steroid-based medications and therapies is common for many autoimmune diseases, but these necessary treatments can have side effects that damage healthy tissue and affect physical health in the long run.

  • Activate & recruit tissue specific cells
  • Reduce inflammation
  • Regulate immune responses
  • Limit and remodel scarring
  • Multiple sclerosis
  • Diabetes
  • Lupus
  • Crohn's disease
  • Rheumatoid arthritis
  • Chronic inflammatory demyelinating polyneuropathy (CIDP)
  • Phemphigus
  • Dermatomyositis
  • Devic disease
  • Myasthenia gravis
  • Polymositis
  • Scleroderma
  • Psoriasis

Stem Cell IV

Stem cells for Autoimmune diseases are typically given intravenously (IV) over the course of a few days.

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Autoimmune & Degenerative Diseases

New treatments and advances in stem cell research are giving new hope to people affected by Autoimmune Diseases. Stem cell therapy for Autoimmune Diseases is being studied for efficacy in improving the complications in patients using stem cells. These autoimmune disorder treatments may help patients who don’t respond to typical drug treatment or want to reduce their reliance on medication.

While stem cells may not be the cure for autoimmunity, they have the potential to reduce symptom outburst and slow or control the progression of different diseases.  Medicinal signaling cells (MSCs) have been shown in studies to contain immunomodulatory effects, systemic administration of these cells may mitigate some symptoms experienced by those who suffer from autoimmune diseases.  These stem cells also have the capacity to reduce inflammation, which can help those with diseases where too much inflammation is a cause of symptoms.

Multiple Sclerosis is a progressive disease of the central nervous system that interferes with the brain's ability to send and receive messages. It is believed to be a result of immune-system dysfunction. Inflammation occurs in the breakdown of myelin, the protective insulation surrounding the nerve fibers of the central nervous system. Myelin is destroyed and replaced by scars of hardened patches of tissue. When the myelin is damaged, nerve impulses are not quickly and efficiently transmitted.

Symptoms of multiple sclerosis vary widely, They may include:

  • Fatigue
  • Impaired vision
  • Loss of balance and muscle coordination
  • Slurred speech
  • Tremors and stiffness
  • Bladder and bowel problems
  • Difficulties with gait (balance or walk), and in severe cases, paralysis.

 

While there is currently no cure for MS, stem cell therapy is a promising new approach to address debilitating MS symptoms while targeting nerve cell repair by making use of the powerful healing mechanisms of your own body.

Stem Cell Therapy for MS

Stem cells known as mesenchymal stem cells, or MSCs have powerful healing properties. They not only stimulate nerve tissue repair, but help to immediately calm inflammation and prevent further nerve cell death.

MSCs can detect changes in the body which are causing pain or dysfunction and can signal the body to provide the correct tools needed for healing. Stem cell therapy can immediately address the debilitating symptoms while getting to work on a more long-term strategy of healing and repair. Stem cells are commonly referred to as “Medicinal Signaling Cells” for this ability to heal injured tissues, organs or body parts, their primary functions being:

  • Decreased inflammation
  • Stimulated cell and tissue regeneration
  • Prevention of further cell death
  • Reduction of scar tissue that prevents normal organ function
  • Stimulate the creation of new blood vessels

 

Improvements that have been seen in MS patients treated with stem cells include:

  • Increased energy
  • Improved memory
  • Better balance and coordination
  • Improved gait and mobility
  • Increased sexual function
  • Reduced medications

According to the Centers for Disease Control (CDC) a growing problem in the United States and worldwide, is the increase of new Lyme disease cases. Lyme disease is caused by the Borrelia bacteria, typically through a tick bite, and can result in fatigue, chronic pain and joint pain that doesn’t respond to conventional therapy.

While antibiotics can cure most cases of Lyme disease, patients might still have muscle or joint pain and nervous system symptoms. This is called post-treatment Lyme disease syndrome (PTLDS).

Stem Cell Therapy for Lyme Disease

Adult stem cells offer real hope to patients suffering from the symptoms of Lyme disease. Treatment of three-to-five rounds of stem cell therapy to cure the disease is recommended.

Stem cell therapy can help:

 

  • Reduce inflammation
  • Minimize pain
  • Regulate immune responses
  • Aid in attacking the Borrelia bacteria

Psoriasis is an autoimmune disease affecting about 2% of the population worldwide and approximately 7.5 million people in the United States. Psoriasis patients present with erythematous scaly well-defined plaques, with the scalp, knees, elbows, hands, and feet being the most commonly affected areas. Approximately 20% of psoriasis patients present with moderate to severe psoriasis with more than 5% of the body surface affected. Fifteen percent of patients with psoriasis will develop psoriatic arthritis, occasionally with joint complaints such as dactylitis, sacroiliitis, enthesopathy, and spondylitis, occurring before cutaneous psoriasis. This condition can cause joint destruction due to the chronic inflammation.

Mesenchymal Stem Cells or Medicinal Signaling Cells (MSCs) have immunomodulatory properties and can stimulate a healing response by reducing inflammation. For this reason, MSCs may be beneficial for patients experiencing excessive inflammation, as is present in autoimmune diseases like psoriasis. Stem cells may reduce the inflammatory response in psoriasis by affecting the epidermis and regulating T cells.

Rheumatoid arthritis is a chronic inflammatory disorder that occurs when the human immune system attacks its own tissues by mistake. This autoimmune disorder mostly impacts the lining of small joints in hands and feet. Eventually, the inflamed lining will cause a painful swelling that can lead to bone erosion and joint deformity.

The disorder can affect people of all ages but is most prevalent in those over 40 and is found more commonly in women. The earliest signs of rheumatoid arthritis appear within the smallest joints first, like fingers and toes. Once the condition has been identified, it can come and go in various stages called “flares.” Some symptoms include tender joints, morning stiffness, fatigue, fever, and weight loss. There is no known cure available.

Thanks to the immunomodulatory and anti-inflammatory properties of mesenchymal stem cells, they hold promise in the treatment of RA. MSCs have been shown to suppress immune responses and regulate inflammation. MSCs have also been shown to reduce the presence of pathogenic T-cells and induce the generation or activation of regulatory T cells.

 

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