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Autism, kid looking far away without interesting

Autism, or Autism Spectrum Disorder (ASD) is a complex disability which affects development with a wide range of signs and symptoms. It impairs the way a person communicates and the way they perceive and interact with the world around them. The condition is described as a spectrum disorder; this means that although some people may share some of the characteristics associated with being autistic, the way each individual is affected can vary. This means that no two children with autism are exactly alike, however, they may share commonalities such as difficulties with language and social interactions.

While many people with the condition lead independent lives others can require a lifetime of support because of the severity in which they have been affected by learning disabilities.

The causes of autism are not yet fully understood and are still under investigation; however, research suggests that genetic and environmental factors may account for changes in brain development. A dysfunctional immune system may have affected the development and operation of the nervous system in some children with the condition. Steroids and anti-inflammatories have had some promise in studies as a symptomatic therapy for autism.

Scientists are hoping to find new treatments that "calm" this overactive immune response to help protect the developing brain in young children with autism.

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Autism

There is currently no cure for those with ASD; however, stem cells could offer some hope. Umbilical cord stem cells infusions could help improve the behavior and language of the children in the trial by modulating inflammatory responses in the brain.

There is evidence to suggest that some children with the condition have dysfunctional immune systems which may be delaying the development or damaging the nervous system.

 

Mesenchymal Stem Cells, or as they are being called now, Medicinal Signaling cells (MSCs) may have unique advantages:

  • Anti-inflammatory properties: Early research has shown that cells found in cord blood can regulate inflammation and migrate to the site of neurologic injury.
  • Bystander effect: The working theory is that the infused cells secrete factors that promote the body's own repair mechanism in the surrounding tissue(s) via paracrine signaling, or what is commonly referred to as the bystander effect.
  • Safe and accessible: Cord blood can be easily collected at the time of birth and stored for potential future use by the newborn donor or close family member.

 

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